【IL 13】重组人白介素-13

产品报价

￥800/2μg ￥2080/10μg ￥74880/1mg

背景资料

IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL-13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechani***s independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

产品描述

人白介素-13重组蛋白是在大肠***中重组表达的，是一条单链、非糖基化的多肽链，包含有112个氨基酸，分子量为12kDa。该人白介素-13重组蛋白***终由标准的色谱技术纯化出。

来源宿主

大肠***中重组表达

序列

GPVPPSTALRELIEELVNITQNQKAPLCNG***VWSINLTAGMYCAALESLINVS GCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRDTKIEVAQFVKDLLLHLKKLFRE GRFN.

溶解建议

提供的人白介素-13(IL 13)产品为过滤灭菌的白色冻干粉末；该冻干粉末是从含1mg/ml人白介素-13(IL 13)的1X PBS（pH 7.2）溶液中冻干产生的。我们建议加无菌的18MΩ-cm水以配制工作储存液到100μg/ml，后继实验过程中可根据实验要求进一步稀释。

保存建议

人白介素-13(IL 13)在室温可保存3周，或置于-18℃冻存用于长期保存。重新溶解后可以在4℃冷藏保存至少2-7天；如果想延长保存时间，建议分装（加载体蛋白如0.1% HSA或 BSA）后置于-18℃冻存。请避免反复冻融。