中文名称: |
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英文名称: |
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其他名称: |
Apoptosis regulator Bcl 2; Apoptosis regulator Bcl2; AW986256; B cell CLL/lymphoma 2; B cell leukemia/lymphoma 2; B cell lymphoma 2; Bcl 2; Bcl-2; Bcl2; BCL2 protein; ***30015F12Rik; D630044D05Rik; D830018M01Rik; Leukemia/lymphoma, B-cell, 2; Oncogene B-cell leukemia 2. |
产品品牌: |
Pllabs |
产品编号: |
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产品规格: |
0.1mg/0.2mg |
产品包装: |
一支包装(原装进口、进口分装) |
免 疫 原: |
KLH conjugated synthetic peptide derived from human Bcl-2 C-terminus |
***类型: |
Rabbit Polyclonal IgG |
背景介绍: |
The Bcl-2 gene was isolated at the chromosomal breakpoint of t(14;18)-bearing follicular B cell lymphomas(1,2).Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal (3,5).Bcl-2 appears to function in several subcellular locati*** yet lacks any known motifs that would confer insight into its mechani*** of action (6,7).A more recently identified protein,designated Bax p21(i.e., Bcl-associated X protein ),has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2(8). Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activty of Bcl-2(8). |
应用范围: |
hu, mo, rat, cow, pig, dog, chk. |
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