中文名称: |
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英文名称: |
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其他名称: |
pigment epithelium-derived factor; Serpin-F1; Stromal cell-derived factor 3; SDF-3; Caspin; Alpha 2 antipla***in; EPC 1; EPC1; PIG 35; PIG35; Pigment epithelium derived factor; Proliferation inducing protein 35; SERPIN F1; Serpin peptidase inhibitor clade F member 1; SERPINF 1; SERPINF1. |
产品品牌: |
Pllabs |
产品编号: |
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产品规格: |
0.1mg/0.2mg |
产品包装: |
一支包装(原装进口、进口分装) |
免 疫 原: |
KLH conjugated synthetic peptide derived from human PEDF C-terminus |
***类型: |
Rabbit Polyclonal IgG |
背景介绍: |
Pigment epithelium derived factor, originally identified in conditioned medium of cultured human fetal retinal pigment epithelial (RPE) cells, is a neurotrophic protein that induces extensive neuronal differentiation in human Y79 retinoblastoma cells, a neoplastic counterpart of normal retinoblasts. It has been suggested that PEDF is synthesized by RPE cells and secreted into the retina interphotoreceptor matrix where it may influence development/differentiation of the neural retina. PEDF is a potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. The PEDF gene is a member of the serpin gene family. Serpins are a group of serine protease inhibitors, some of which h***e also been reported to exhibit neurotrophic activity. |
应用范围: |
Human, Mouse, Rat, Dog, Pig, Cow,(Please decide the specificity by homology) |
更多产品: |
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